NEUROVASCULAR COUPLING IN THE CEREBELLAR GRANULAR LAYER
نویسندگان
چکیده
منابع مشابه
Granular Layer Neurons Control Cerebellar Neurovascular Coupling Through an NMDA Receptor/NO-Dependent System.
Neurovascular coupling (NVC) is the process whereby neuronal activity controls blood vessel diameter. In the cerebellum, the molecular layer is regarded as the main NVC determinant. However, the granular layer is a region with variable metabolic demand caused by large activity fluctuations that shows a prominent expression of NMDA receptors (NMDARs) and nitric oxide synthase (NOS) and is theref...
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متن کاملNeurovascular coupling - Scholarpedia
Neurovascular coupling refers to the relationship between local neural activity and subsequent changes in cerebral blood flow (CBF). The magnitude and spatial location of blood flow changes are tightly linked to changes in neural activity through a complex sequence of coordinated events involving neurons, glia, and vascular cells. Many vascular-based functional brain imaging techniques, such as...
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In the adult central nervous system (CNS), gamma-amino butyric acid (GABA) is a predominant inhibitory neurotransmitter, which regulates glutamatergic activity. Recent studies have revealed that GABA serves as an excitatory transmitter in the immature CNS, and is involved in brain morphogenesis. To elucidate how GABA exerts its effect on immature neurons and how GABAergic synapses are formed, w...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2017
ISSN: 1662-5102
DOI: 10.3389/conf.fncel.2017.37.00008